Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 15/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.58 |
| ▸ | HRH2 | P25021 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563214 | 0.86 | BCHE (0.56) | HRH3HRH2HRH1 | |
| SCHEMBL9032176 | 0.83 | CHRM2 (0.68) | MEN1HRH3HRH2HRH1KMT2A | |
| SCHEMBL16307566 | 0.82 | MEN1 (0.63) | MEN1HRH3HRH2HRH1KMT2A | |
| SCHEMBL9047533 | 0.82 | BCHE (0.59) | HRH3HRH2HRH1 | |
| SCHEMBL9563324 | 0.81 | BCHE (0.69) | HRH3 | |
| SCHEMBL9033163 | 0.80 | BCHE (0.66) | MEN1HRH2HRH1KMT2A | |
| SCHEMBL9563314 | 0.79 | BCHE (0.53) | MEN1HRH3HRH2HRH1KMT2A | |
| SCHEMBL9186128 | 0.79 | MEN1 (0.67) | MEN1HRH3HRH2HRH1KMT2A | |
| SCHEMBL9563267 | 0.79 | BCHE (0.53) | MEN1HRH3HRH2HRH1KMT2A | |
| SCHEMBL9031522 | 0.77 | HPGDS (0.54) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | claimed |
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5225559-A | DIARYLMETHOXYPIPERIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0485984-A2 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |