Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.68 |
| ▸ | DRD1 | P21728 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 2/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | MLNR | O43193 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.68 |
| ▸ | FYN | P06241 | 1/20 | 0.68 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031262 | 0.89 | HRH3 (0.55) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9563214 | 0.85 | BCHE (0.56) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL6385060 | 0.83 | KCNH2 (0.70) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10762463 | 0.83 | KCNH2 (0.70) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9031877 | 0.83 | MEN1 (0.60) | HRH2HRH1HRH3MEN1KMT2A | |
| Ebastine SCHEMBL18467 | 0.81 | ADRA1D (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9033163 | 0.81 | BCHE (0.66) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL4025471 | 0.81 | BCHE (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL12142390 | 0.81 | CHRM2 (0.60) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9563324 | 0.81 | BCHE (0.69) | BCHEHRH3PARP14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | claimed |