SCHEMBL9032115

SCHEMBL9032115

CCOC(NC=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.39
ADH1A P07327 3/20 0.39
ADH1C P00326 2/20 0.39
THRB P10828 1/20 0.36
ADH7 P40394 2/20 0.35
ADH4 P08319 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531441 0.77
SCHEMBL1749291 0.72 ADH1B (0.39) ADH1BADH1AADH1CTHRBADH7
SCHEMBL7530506 0.70 ADH1B (0.37) ADH1BADH1AADH1CADH7ADH4
SCHEMBL9032142 0.69
SCHEMBL7523847 0.69 ADH1B (0.36) ADH1BADH1AADH1CADH7ADH4
SCHEMBL8314908 0.67 THRB (0.47) THRBLMNA
SCHEMBL3812345 0.65
SCHEMBL13694800 0.65 ADH1B (0.48) ADH1BADH1AADH1CTHRBADH7
SCHEMBL23780006 0.65 ADH1B (0.34) ADH1BADH1AADH1CADH7ADH4
SCHEMBL7000942 0.64 ADH1B (0.36) ADH1BADH1AADH1CADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101460198-B Thermosensitive polyphosphazene-bioactive molecule conjugate, preparation method and application thereof KOREA INST SCI & TECH 2013-08-07 CN disclosed
CN-101460198-A Thermosensitive polyphosphazene-bioactive molecule conjugate, preparation method and application thereof KOREA INST SCI & TECH (KR) 2009-06-17 CN disclosed
CN-101360513-A Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof KOREA INST SCI & TECH (KR) 2009-02-04 CN disclosed
EP-0705835-A1 Quinoxalic-2,3-diones with an oxa or thiaheterocyclic fused ring CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed