Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264984 | 0.92 | PPARG (0.43) | PPARGAGTR1AGTR2 | |
| SCHEMBL9033453 | 0.87 | PPARG (0.43) | PPARGAGTR1AGTR2ALDH1A1KDM4E | |
| SCHEMBL9032771 | 0.86 | PPARG (0.43) | PPARGAGTR1AGTR2ALDH1A1AR | |
| SCHEMBL9030796 | 0.86 | PPARG (0.44) | PPARGAGTR1AGTR2ALDH1A1KDM4E | |
| SCHEMBL9032562 | 0.85 | PPARG (0.44) | PPARGAGTR1AGTR2ALDH1A1AR | |
| SCHEMBL7016142 | 0.85 | AGTR1 (0.39) | PPARGAGTR1AGTR2 | |
| SCHEMBL7016159 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2ALDH1A1KDM4EHPGD | |
| SCHEMBL9032906 | 0.84 | PPARG (0.43) | PPARGAGTR1AGTR2ALDH1A1KDM4E | |
| SCHEMBL9031954 | 0.84 | PPARG (0.45) | PPARGAGTR1AGTR2ALDH1A1AR | |
| SCHEMBL9031592 | 0.84 | PPARG (0.44) | PPARGAGTR1AGTR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |