Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032771 | 0.92 | PPARG (0.43) | PPARGALDH1A1ARTDP1AGTR1 | |
| SCHEMBL9031954 | 0.91 | PPARG (0.45) | PPARGALDH1A1ARTDP1AGTR1 | |
| SCHEMBL9032562 | 0.91 | PPARG (0.44) | PPARGALDH1A1ARTDP1AGTR1 | |
| SCHEMBL9030796 | 0.88 | PPARG (0.44) | PPARGALDH1A1ARTDP1KDM4E | |
| SCHEMBL9032306 | 0.87 | PPARG (0.42) | PPARGALDH1A1ARTDP1KDM4E | |
| SCHEMBL9032906 | 0.86 | PPARG (0.43) | PPARGALDH1A1ARTDP1KDM4E | |
| SCHEMBL9031469 | 0.86 | PPARG (0.43) | PPARGALDH1A1ARTDP1AGTR1 | |
| SCHEMBL9033410 | 0.82 | AGTR1 (0.40) | ALDH1A1TDP1KDM4EGLAGAA | |
| SCHEMBL7016745 | 0.82 | PPARG (0.37) | PPARGALDH1A1TDP1KDM4EGLA | |
| SCHEMBL9031128 | 0.82 | PPARG (0.54) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |