Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 19/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 19/20 | 0.54 |
| ▸ | TLR3 | O15455 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868243 | 0.86 | HIF1A (0.54) | HIF1AEPAS1TLR3 | |
| SCHEMBL9032078 | 0.85 | HIF1A (0.53) | HIF1AEPAS1 | |
| Eulatachromene SCHEMBL9033640 | 0.85 | HIF1A (0.53) | HIF1AEPAS1TLR3 | |
| SCHEMBL507142 | 0.85 | HIF1A (0.53) | HIF1AEPAS1TLR3 | |
| SCHEMBL14930294 | 0.82 | HIF1A (0.64) | HIF1AEPAS1 | |
| SCHEMBL14930293 | 0.82 | HIF1A (0.61) | HIF1AEPAS1 | |
| SCHEMBL14541294 | 0.81 | HIF1A (0.56) | HIF1AEPAS1 | |
| SCHEMBL2825117 | 0.80 | HIF1A (0.52) | HIF1AEPAS1 | |
| SCHEMBL9475843 | 0.79 | ALDH1A1 (0.45) | HIF1AEPAS1TLR3 | |
| SCHEMBL5808068 | 0.79 | HIF1A (0.48) | HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453837-B1 | Substituted pyridazinones, process for their preparation and their use as parasiticide | BAYER AG (DE) | 1996-06-19 | — | — | EP | disclosed |
| US-5141939-A | PESTICIDAL CHROMEN-6-YL-METHYL-OXY-AND-THIAPYRIZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| EP-0453837-A2 | Substituted pyridazinones, process for their preparation and their use as parasiticide | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |