Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033912 | 0.92 | ITGB3 (0.41) | ITGB3ITGAVITGB5SLC6A2 | |
| SCHEMBL9034267 | 0.89 | ITGB3 (0.41) | ITGB3ITGAVITGB5SLC6A2 | |
| SCHEMBL9033809 | 0.86 | SLC6A2 (0.46) | ITGB3ITGAVITGB5SLC6A2 | |
| SCHEMBL9033182 | 0.86 | ITGB3 (0.35) | ITGB3ITGAVITGB5OXER1 | |
| SCHEMBL9034237 | 0.86 | CACNA1H (0.36) | SLC6A2 | |
| SCHEMBL9033330 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVOXER1 | |
| SCHEMBL9465390 | 0.85 | OXER1 (0.38) | ITGB3ITGAVOXER1 | |
| SCHEMBL9033452 | 0.84 | — | — | |
| SCHEMBL9033432 | 0.84 | — | — | |
| SCHEMBL9034046 | 0.84 | ITGB3 (0.40) | ITGB3ITGAVOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |