Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033912 | 0.94 | ITGB3 (0.41) | SLC6A2SLC6A4ITGB3ITGAVITGB5 | |
| SCHEMBL9034267 | 0.93 | ITGB3 (0.41) | SLC6A2SLC6A4ITGB3ITGAVITGB5 | |
| SCHEMBL9034512 | 0.91 | ITGB3 (0.41) | SLC6A2SLC6A4ITGB3ITGAVITGB5 | |
| SCHEMBL9033253 | 0.89 | SLC6A2 (0.38) | SLC6A2SLC6A4ITGB3ITGAVITGB5 | |
| SCHEMBL9031283 | 0.87 | ITGB3 (0.39) | ITGB3ITGAVITGB5 | |
| SCHEMBL9033860 | 0.87 | ITGB3 (0.44) | ITGB3ITGAV | |
| SCHEMBL9033445 | 0.86 | ITGB3 (0.35) | SLC6A2ITGB3ITGAVITGB5 | |
| SCHEMBL9032615 | 0.86 | BRD4 (0.38) | ITGB3ITGAV | |
| SCHEMBL9031376 | 0.86 | ITGB3 (0.40) | SLC6A2SLC6A4ITGB3ITGAVITGB5 | |
| SCHEMBL9034483 | 0.85 | ITGB3 (0.37) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |