Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033466 | 0.82 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL9032005 | 0.79 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL5674913 | 0.79 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL5674922 | 0.79 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL1199326 | 0.78 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL11985482 | 0.78 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL20027984 | 0.77 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL22896950 | 0.77 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL11985494 | 0.77 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL23965741 | 0.76 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528734-B1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-10-23 | — | — | EP | claimed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | claimed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | claimed |