Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624262 | 0.81 | GABRA1 (0.41) | CYSLTR2CYSLTR1ADRA2AADRA2BTSHR | |
| SCHEMBL7643940 | 0.77 | ADRA2A (0.44) | CYSLTR2CYSLTR1ADRA2AADRA2BADRA2C | |
| SCHEMBL872725 | 0.77 | ADRA2A (0.44) | CYSLTR2CYSLTR1ADRA2AADRA2BADRA2C | |
| SCHEMBL4843352 | 0.77 | ADRA2A (0.46) | CYSLTR2CYSLTR1ADRA2AADRA2BADRA2C | |
| SCHEMBL9621039 | 0.77 | ADRA2A (0.46) | CYSLTR2CYSLTR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6901338 | 0.76 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PPARAPPARG | |
| SCHEMBL4615949 | 0.76 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARAPPARG | |
| SCHEMBL4029728 | 0.75 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1PPARAPPARG | |
| SCHEMBL27842150 | 0.75 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PPARAPPARG | |
| SCHEMBL28373053 | 0.75 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013116200-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| WO-2012044832-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | FETZER OLIVER S (US) | 2012-04-05 | — | — | WO | disclosed |