SCHEMBL9033719

SCHEMBL9033719

CCOc1ccccc1CNCc1ccccc1OCC

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.73
ALDH1A1 P00352 5/20 0.72
KDM4E B2RXH2 2/20 0.63
L3MBTL1 Q9Y468 4/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
MAPT P10636 3/20 0.60
GAA P10253 3/20 0.60
ATM Q13315 2/20 0.60
POLB P06746 1/20 0.60
THRB P10828 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
PLEC Q15149 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
NPSR1 Q6W5P4 1/20 0.58
CYP2D6 P10635 1/20 0.56
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10282637 0.92 ALDH1A1 (0.68) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL30877044 0.91 MAPK1 (0.77) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL27312115 0.91 MAPK1 (0.77) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL27313687 0.88 MAPK1 (0.78) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL1254288 0.86 ALDH1A1 (0.60) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL172677 0.86 ALDH1A1 (0.67) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL1521207 0.84 ALDH1A1 (0.63) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL15782766 0.84 ALDH1A1 (0.65) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL2734546 0.84 ALDH1A1 (0.60) MAPK1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL2399873 0.83 ALDH1A1 (0.58) MAPK1ALDH1A1KDM4EL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190248958-A1 PREPARATION METHOD OF OLIGOMER ADDITIVE, OLIGOMER ADDITIVE, AND LITHIUM BATTERY NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2019-08-15 US disclosed
EP-0696593-A2 Inhibitors of farnesyl protein transferase BRISTOL-MYERS SQUIBB COMPANY (US) 1996-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248958-A1 PREPARATION METHOD OF OLIGOMER ADDITIVE, OLIGOMER ADDITIVE, AND LITHIUM BATTERY PCNA, SCO2, PARG MAPK1 2264/4885ALDH1A1 3550/4885KDM4E 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.