Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995912 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL9033719 | 0.86 | MAPK1 (0.73) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL18997832 | 0.83 | GAA (0.68) | ALDH1A1L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10282637 | 0.82 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL12000665 | 0.79 | L3MBTL1 (0.67) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL27313687 | 0.79 | MAPK1 (0.78) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL30877044 | 0.78 | MAPK1 (0.77) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL27312115 | 0.78 | MAPK1 (0.77) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL1254288 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1ATMPOLB | |
| SCHEMBL12461613 | 0.77 | L3MBTL1 (0.56) | ALDH1A1MAPK1L3MBTL1ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |