Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033839 | 0.95 | KMT2A (0.40) | TACR1KMT2ACETPABCB1PSMB5 | |
| SCHEMBL9033588 | 0.93 | ABCB1 (0.40) | TACR1KMT2AABCB1PLA2G4APLA2G6 | |
| SCHEMBL9035133 | 0.92 | ABCB1 (0.39) | TACR1KMT2AABCB1GHSRPLA2G4A | |
| SCHEMBL9032745 | 0.88 | ABCB1 (0.39) | TACR1KMT2AABCB1GHSRPLA2G4A | |
| SCHEMBL9033888 | 0.88 | ABCB1 (0.41) | KMT2AABCB1PLA2G4APLA2G6 | |
| SCHEMBL9033581 | 0.87 | ABCB1 (0.42) | KMT2AABCB1TSHR | |
| SCHEMBL9035126 | 0.87 | ABCB1 (0.40) | TACR1KMT2AABCB1GHSRPLA2G4A | |
| SCHEMBL9034510 | 0.86 | ABCB1 (0.37) | TACR1KMT2AABCB1PLA2G4APLA2G6 | |
| SCHEMBL9034867 | 0.86 | ABCB1 (0.35) | TACR1KMT2AABCB1PLA2G4APLA2G6 | |
| SCHEMBL9033882 | 0.84 | ABCB1 (0.42) | KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |