Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031843 | 0.79 | NPSR1 (0.53) | HCAR2SMN1; SMN2ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL12431015 | 0.75 | — | — | |
| SCHEMBL1740 | 0.75 | — | — | |
| SCHEMBL11707587 | 0.75 | — | — | |
| SCHEMBL9033677 | 0.75 | — | — | |
| SCHEMBL23829843 | 0.75 | — | — | |
| SCHEMBL1739 | 0.75 | — | — | |
| SCHEMBL11708371 | 0.75 | HCAR2 (0.46) | TSHRHCAR2KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL2326353 | 0.73 | SMN1; SMN2 (0.50) | TSHRHCAR2KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL2326348 | 0.73 | SMN1; SMN2 (0.50) | TSHRHCAR2KEAP1NFE2L2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705835-A1 | Quinoxalic-2,3-diones with an oxa or thiaheterocyclic fused ring | CIBA-GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |