Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.65 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087274 | 0.98 | FAAH (0.68) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL4276745 | 0.98 | FAAH (0.68) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL28417636 | 0.98 | FAAH (0.68) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL4439946 | 0.98 | FAAH (0.68) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL7346940 | 0.94 | CASP2 (0.66) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL3033459 | 0.94 | CASP2 (0.66) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL3033120 | 0.94 | CASP2 (0.59) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL10443771 | 0.92 | CASP2 (0.69) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL10895513 | 0.92 | CASP2 (0.69) | FAAHCASP2DNM1NAAAEPHX2 | |
| SCHEMBL7557154 | 0.92 | CASP2 (0.69) | FAAHCASP2DNM1NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| US-4786649-A | ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0228035-A2 | Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylix acid compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |