Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.34 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034138 | 0.89 | PLA2G4A (0.36) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034739 | 0.89 | ABCB1 (0.41) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034732 | 0.89 | ABCB1 (0.41) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034722 | 0.89 | ABCB1 (0.41) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034729 | 0.89 | ABCB1 (0.41) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034508 | 0.88 | ABCB1 (0.39) | ABCB1KMT2AMEN1PLA2G4APLA2G6 | |
| SCHEMBL9034024 | 0.88 | ABCB1 (0.39) | ABCB1KMT2APLA2G4APLA2G6KDM4E | |
| SCHEMBL9033882 | 0.88 | ABCB1 (0.42) | ABCB1KMT2AMEN1POLBHDAC8 | |
| SCHEMBL9033581 | 0.88 | ABCB1 (0.42) | ABCB1KMT2AMEN1POLBHDAC8 | |
| SCHEMBL9035892 | 0.86 | ABCB1 (0.37) | ABCB1KMT2AMEN1PLA2G4APLA2G6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |