Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034095 | 0.78 | ALOX15 (0.36) | HRH3CYP2D6CYP1A2MAPK1POLB | |
| SCHEMBL9035300 | 0.76 | CYP1A2 (0.33) | CYP2D6CYP1A2MAPK1 | |
| SCHEMBL9034996 | 0.75 | HRH3 (0.43) | HRH3CYP2D6CYP2C9HIF1ATDP1 | |
| SCHEMBL9032167 | 0.74 | HRH3 (0.44) | HRH3CYP2D6CYP2C9HIF1ATDP1 | |
| SCHEMBL8701115 | 0.66 | KMT2A (0.36) | HRH3CYP2D6CYP1A2MAPK1POLB | |
| SCHEMBL9032686 | 0.66 | HRH3 (0.41) | HRH3LMNATDP1ALDH1A1KDM4E | |
| SCHEMBL10673019 | 0.65 | CYP1A2 (0.39) | HRH3CYP2D6CYP1A2MAPK1POLB | |
| SCHEMBL9033441 | 0.65 | HRH3 (0.43) | HRH3LMNATDP1ALDH1A1KDM4E | |
| SCHEMBL27445054 | 0.63 | HRH3 (0.41) | HRH3CYP2D6CYP2C9HIF1ATDP1 | |
| SCHEMBL9032093 | 0.63 | SMN1; SMN2 (0.33) | HRH3POLBADRA1AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |