Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12521604 | 0.84 | GABRA1 (0.40) | POLBALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL8346413 | 0.84 | GABRA1 (0.40) | POLBALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL27851029 | 0.82 | PPARG (0.44) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL12520102 | 0.82 | GABRA1 (0.39) | POLBALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL19143283 | 0.78 | GABRA1 (0.43) | POLBALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL12880104 | 0.78 | HPGD (0.56) | POLBALDH1A1TSHRSLC6A2SLC6A4 | |
| SCHEMBL2625209 | 0.78 | HPGD (0.56) | POLBALDH1A1TSHRSLC6A2SLC6A4 | |
| SCHEMBL13692275 | 0.77 | GABRA1 (0.44) | POLBALDH1A1GABRA1GABRB2L3MBTL1 | |
| SCHEMBL8520662 | 0.77 | APAF1 (0.59) | POLBTSHRMAPTKDM4EAPAF1 | |
| SCHEMBL3459705 | 0.77 | GABRA1 (0.44) | POLBALDH1A1GABRA1GABRB2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044832-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | FETZER OLIVER S (US) | 2012-04-05 | — | — | WO | disclosed |
| WO-2011146638-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASES | CERULEAN PHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |