Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831999 | 0.85 | L3MBTL1 (0.50) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832096 | 0.81 | L3MBTL1 (0.48) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL12086511 | 0.79 | NQO2 (0.59) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832020 | 0.74 | MEN1 (0.54) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832235 | 0.71 | MEN1 (0.47) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832163 | 0.70 | MEN1 (1.00) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832276 | 0.70 | KMT2A (0.64) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL28343024 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL8831953 | 0.68 | MEN1 (0.55) | MEN1KMT2ANR1I2AHRMAPT | |
| SCHEMBL8832521 | 0.68 | MEN1 (0.55) | MEN1KMT2ANR1I2AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695754-A1 | INDOLO 2,3-b]QUINOXALINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-02-07 | — | — | EP | disclosed |