Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 13/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034612 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AREN | |
| SCHEMBL9033882 | 0.90 | ABCB1 (0.42) | MEN1KMT2AABCB1HTTATM | |
| SCHEMBL9035167 | 0.87 | CA2 (0.41) | MEN1KMT2AABCB1HTT | |
| SCHEMBL9034024 | 0.87 | ABCB1 (0.39) | KMT2AABCB1 | |
| SCHEMBL9034508 | 0.86 | ABCB1 (0.39) | MEN1KMT2ARENABCB1ATM | |
| SCHEMBL9033581 | 0.85 | ABCB1 (0.42) | MEN1KMT2AABCB1ATM | |
| SCHEMBL9034415 | 0.85 | ABCB1 (0.41) | SMN1; SMN2ALDH1A1KMT2AABCB1 | |
| SCHEMBL9034739 | 0.85 | ABCB1 (0.41) | MEN1KMT2AABCB1 | |
| SCHEMBL9034732 | 0.85 | ABCB1 (0.41) | MEN1KMT2AABCB1 | |
| SCHEMBL9034729 | 0.85 | ABCB1 (0.41) | MEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |