Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186244 | 0.96 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL18237266 | 0.88 | NPC1 (0.55) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL24511331 | 0.87 | TSHR (0.54) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL14174892 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL24510719 | 0.82 | TSHR (0.50) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL24511015 | 0.80 | LMNA (0.48) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL18198060 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4ENPC1HRH3EPHX1 | |
| SCHEMBL24511018 | 0.79 | TSHR (0.47) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL14303959 | 0.78 | HRH3 (0.45) | ALDH1A1KDM4EMAPK1NPC1LMNA | |
| SCHEMBL18198134 | 0.77 | KDM4E (0.54) | ALDH1A1KDM4ENPC1HRH3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |