Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 3/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213359 | 1.00 | KCNH2 (0.61) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9819846 | 1.00 | KCNH2 (0.61) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9819966 | 1.00 | KCNH2 (0.61) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9038087 | 0.96 | KCNH2 (0.56) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9819824 | 0.96 | KCNH2 (0.56) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9819747 | 0.96 | KCNH2 (0.56) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL10444157 | 0.96 | KCNH2 (0.56) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9820041 | 0.92 | NAAA (0.55) | KCNH2NAAAMIFSIGMAR1 | |
| SCHEMBL9819988 | 0.92 | SIGMAR1 (0.52) | KCNH2NAAAMIFSIGMAR1HTR2A | |
| SCHEMBL9212818 | 0.92 | SIGMAR1 (0.52) | KCNH2NAAAMIFSIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |