⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174338 | 0.83 | NFE2L2 (0.33) | — | |
| SCHEMBL18174374 | 0.83 | NFE2L2 (0.33) | — | |
| SCHEMBL14491906 | 0.81 | CYP3A4 (0.33) | — | |
| SCHEMBL4380039 | 0.78 | F2 (0.38) | — | |
| SCHEMBL17505083 | 0.74 | NFE2L2 (0.42) | — | |
| SCHEMBL17507307 | 0.71 | NFE2L2 (0.64) | — | |
| SCHEMBL13208008 | 0.70 | — | — | |
| SCHEMBL3211868 | 0.68 | NPC1 (0.31) | — | |
| SCHEMBL4543421 | 0.68 | ALDH1A1 (0.38) | — | |
| SCHEMBL18174344 | 0.68 | NFE2L2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199523-A1 | THE NEW PROCESS FOR PRODUCING N-PHENYL-N-(4-PIPERIDINYL) AMIDE DERIVATIVES SUCH AS REMIFENTANIL AND CARFENTANIL | Bioka s. r.o. (SK) | 2017-08-02 | — | — | EP | claimed |
| EP-0315405-B1 | 4-phenyl-4-(N-(2-fluorophenyl)amido) piperidine derivatives | OHMEDA PHARMA PROD (US) | 1996-01-24 | — | — | EP | claimed |
| EP-3199523-A1 | THE NEW PROCESS FOR PRODUCING N-PHENYL-N-(4-PIPERIDINYL) AMIDE DERIVATIVES SUCH AS REMIFENTANIL AND CARFENTANIL | Bioka s. r.o. (SK) | 2017-08-02 | — | — | EP | disclosed |
| EP-0315405-B1 | 4-phenyl-4-(N-(2-fluorophenyl)amido) piperidine derivatives | OHMEDA PHARMA PROD (US) | 1996-01-24 | — | — | EP | disclosed |