Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468764 | 0.84 | KMT2A (0.47) | CES2CES1AKR1B1MEN1FAAH | |
| SCHEMBL9223730 | 0.78 | CES2 (0.52) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL6468759 | 0.78 | CES2 (0.38) | CES2CES1KMT2AALDH1A1 | |
| SCHEMBL14976704 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL28639361 | 0.77 | CES2 (0.56) | CES2CES1AKR1B1MEN1FAAH | |
| SCHEMBL430826 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL2440945 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL2444713 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL14976297 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL430824 | 0.77 | CES2 (0.61) | CES2CES1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737193-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018128-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |