Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468764 | 0.91 | KMT2A (0.47) | CES2CES1MAPTKMT2A | |
| SCHEMBL9034995 | 0.78 | CES2 (0.52) | CES2CES1ALDH1A1KMT2A | |
| SCHEMBL27735593 | 0.74 | CES2 (0.39) | CES2CES1ALDH1A1 | |
| SCHEMBL9532328 | 0.74 | KMT2A (0.43) | CES2CES1ALDH1A1TP53MAPT | |
| SCHEMBL20913016 | 0.73 | CES1 (0.58) | CES2CES1ALDH1A1TP53MAPT | |
| SCHEMBL109288 | 0.73 | — | — | |
| SCHEMBL9533973 | 0.73 | CES2 (0.38) | CES2CES1ALDH1A1MAPTKMT2A | |
| SCHEMBL23736177 | 0.71 | KMT2A (0.61) | CES2CES1ALDH1A1TP53MAPT | |
| SCHEMBL8619284 | 0.71 | CES1 (0.55) | CES2CES1ALDH1A1TP53MAPT | |
| SCHEMBL22110975 | 0.71 | CES1 (0.55) | CES2CES1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |