Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954938 | 0.87 | CHRM1 (0.43) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8054785 | 0.84 | CHRM2 (0.46) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL3424285 | 0.80 | ACHE (0.48) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7321984 | 0.80 | GNAO1 (0.59) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL3954095 | 0.79 | SLC18A3 (0.42) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL3955932 | 0.79 | CHRM2 (0.36) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL706462 | 0.78 | SLC18A3 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL2148991 | 0.78 | GNAO1 (0.53) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL5034030 | 0.76 | CHRM1 (0.49) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL25274547 | 0.76 | CHRM1 (0.38) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |