Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253013 | 0.89 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9037639 | 0.89 | ALOX5 (0.74) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9029002 | 0.88 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL6025633 | 0.87 | ALOX5 (0.66) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9269047 | 0.87 | ALOX5 (0.66) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9046607 | 0.87 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9224252 | 0.87 | ALOX5 (0.68) | ALOX5PTGS1PTGS2 | |
| SCHEMBL6024923 | 0.86 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9229310 | 0.86 | ALOX5 (0.67) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9074025 | 0.85 | ALOX5 (0.63) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570196-B1 | Oxime derivatives | ZENECA LTD (GB) | 1996-03-06 | — | — | EP | disclosed |
| US-5457125-A | Inhibitors of 5-lipoxygenase; antiallergens, antiinflammatory agents | ZENECA LIMITED (GB) | 1995-10-10 | — | — | US | disclosed |
| US-5376680-A | Inhibitors of the enzyme 5-lipoxygenase | ZENECA LIMITED (GB) | 1994-12-27 | — | — | US | disclosed |
| EP-0570196-A1 | Oxime derivatives | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |