Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037639 | 0.89 | ALOX5 (0.74) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9035232 | 0.89 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9029002 | 0.88 | ALOX5 (0.70) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9224252 | 0.87 | ALOX5 (0.68) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9229310 | 0.86 | ALOX5 (0.67) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9046607 | 0.85 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL6025633 | 0.85 | ALOX5 (0.66) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9269047 | 0.85 | ALOX5 (0.66) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9229549 | 0.85 | ALOX5 (0.66) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9228198 | 0.84 | ALOX5 (0.74) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |