Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.67 |
| ▸ | RAB9A | P51151 | 12/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405967 | 0.88 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL11345273 | 0.73 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL11351283 | 0.73 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL11346555 | 0.73 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL11347408 | 0.71 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL6340484 | 0.71 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL6340695 | 0.71 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL13657955 | 0.71 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL6232715 | 0.71 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL29956850 | 0.71 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497367-B1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES (JP) | 1996-07-24 | — | — | EP | claimed |
| EP-0497367-A1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES, LTD. (JP) | 1992-08-05 | — | — | EP | claimed |
| JP-5112546-A | — | — | None | — | — | JP | disclosed |
| EP-0497367-B1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5221685-A | Insecticides, miticides or fungicides | UBE INDUSTRIES, LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| JP-H05112546-A | 1-(THIAZOLIN-2-YL)-3-BENZOYLUREA COMPOUND, ITS PRODUCTION AND HARMFUL LIVING THING CONTROLLING AGENT | UBE IND LTD | 1993-05-07 | — | — | JP | disclosed |
| EP-0497367-A1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES, LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |