Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HTR1D | P28221 | 4/20 | 0.53 |
| ▸ | HTR1B | P28222 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808869 | 0.78 | HTR1D (0.50) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL6812001 | 0.78 | HTR1D (0.53) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8705195 | 0.76 | HTR1D (0.70) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL4336114 | 0.76 | HTR3E (0.69) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL6812249 | 0.76 | MCHR1 (0.61) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL7883944 | 0.74 | POLB (0.55) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL5827458 | 0.74 | HTR1D (0.55) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL6817253 | 0.73 | HTR1A (0.53) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| 4-Chloro-Benzoic Acid SCHEMBL9035256 | 0.73 | HTR1D (0.66) | HTR6HTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8986030 | 0.73 | HTR1D (0.57) | HTR6HTR2CHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712397-A1 | AMIDE DERIVATIVES AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004729-A1 | AMIDE DERIVATIVES AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-16 | — | — | WO | disclosed |