Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245472 | 0.96 | EPHX1 (0.39) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL1559459 | 0.94 | EPHX1 (0.42) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL8579936 | 0.94 | EPHX1 (0.42) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL9034149 | 0.92 | HTT (0.30) | HTT | |
| SCHEMBL4314580 | 0.85 | NAAA (0.39) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL697833 | 0.83 | EPHX1 (0.37) | EPHX1HTTNAAACYP2C19TPSAB1 | |
| SCHEMBL4312944 | 0.83 | NAAA (0.38) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL2901152 | 0.83 | NAAA (0.40) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL4307836 | 0.82 | NAAA (0.40) | EPHX1HTTNAAACYP2C19CYP19A1 | |
| SCHEMBL4307907 | 0.82 | NAAA (0.39) | EPHX1HTTNAAACYP2C19CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |