Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935942 | 0.83 | ALDH1A1 (0.70) | ALDH1A1GAALMNAPLK1RAB9A | |
| SCHEMBL3126897 | 0.82 | LMNA (0.46) | ALDH1A1GAALMNAMAPTHTT | |
| SCHEMBL3406790 | 0.82 | LMNA (0.65) | ALDH1A1GAALMNAPLK1RAB9A | |
| SCHEMBL23391003 | 0.79 | ALDH1A1 (0.64) | ALDH1A1GAALMNAPLK1RAB9A | |
| SCHEMBL10731985 | 0.78 | ALDH1A1 (0.57) | ALDH1A1GAALMNAPLK1NPC1 | |
| SCHEMBL24169719 | 0.77 | ALDH1A1 (0.65) | ALDH1A1GAALMNARAB9ANPC1 | |
| SCHEMBL13683317 | 0.76 | ALDH1A1 (0.67) | ALDH1A1GAALMNAPLK1NPC1 | |
| SCHEMBL7639283 | 0.76 | BCL2L1 (0.48) | ALDH1A1LMNARAB9ANPC1MAPT | |
| SCHEMBL12595805 | 0.75 | ALDH1A1 (0.70) | ALDH1A1LMNAPLK1RAB9ANPC1 | |
| SCHEMBL13057533 | 0.75 | MAPT (0.65) | ALDH1A1GAALMNAPLK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741720-A1 | HETEROCYCLIC CHEMOLUMINESCENT DERIVATIVES | BIOCODE S.A. (BE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995019976-A1 | HETEROCYCLIC CHEMOLUMINESCENT DERIVATIVES | BIOCODE S.A. (BE) | 1995-07-27 | — | — | WO | disclosed |