Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579289 | 0.95 | DNM1 (0.48) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL9170834 | 0.92 | DNM1 (0.52) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL2217865 | 0.92 | S1PR2 (0.39) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL5405623 | 0.87 | DNM1 (0.52) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL7282782 | 0.87 | SIGMAR1 (0.47) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL5391134 | 0.87 | DNM1 (0.52) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL2303995 | 0.86 | — | — | |
| SCHEMBL28107821 | 0.86 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL9371017 | 0.86 | CHRM2 (0.52) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL27456365 | 0.85 | DNM1 (0.39) | S1PR2S1PR1S1PR3S1PR5DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058226-A1 | CONTACT BIOCIDES BASED ON POLY(OXAZINE)S, POLY(OXAZEPINE)S, AND POLY(OXAZOZINE)S | POLYMER COMPETENCE CENTER LEOBEN (AT) | 2015-04-30 | — | — | WO | disclosed |
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5434164-A | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0240015-B1 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMA CO LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |
| US-5008274-A | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0240015-A2 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |