Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7212574 | 0.99 | SETD7 (0.54) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7212597 | 0.87 | SETD7 (0.56) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7213932 | 0.86 | SETD7 (0.58) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| SCHEMBL9034261 | 0.81 | SETD7 (0.54) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7212354 | 0.81 | SETD7 (0.53) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| SCHEMBL12511057 | 0.79 | ACHE (0.74) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9455509 | 0.79 | SETD7 (0.46) | SETD7ACHEALDH1A1KDM4EMEN1 | |
| SCHEMBL9035520 | 0.79 | MEN1 (0.54) | SETD7ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7218937 | 0.78 | CYP1A2 (0.51) | SETD7ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7217856 | 0.78 | CYP1A2 (0.51) | SETD7ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |