Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305124 | 0.91 | ABCG2 (0.41) | FLT3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8427219 | 0.90 | FLT3 (0.45) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL8307487 | 0.84 | FLT3 (0.61) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL4575086 | 0.83 | AKT1 (0.43) | FLT3MAPTPOLBNPC1APP | |
| SCHEMBL8305275 | 0.82 | AKT1 (0.42) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL8306599 | 0.81 | FLT3 (0.47) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL8431289 | 0.79 | ABCB1 (0.50) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL19354052 | 0.79 | FLT3 (0.67) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL5276648 | 0.77 | ALDH1A1 (0.54) | FLT3MAPTMEN1KMT2APOLB | |
| SCHEMBL8427216 | 0.77 | PTGS1 (0.39) | FLT3MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | claimed |