SCHEMBL9035805

SCHEMBL9035805

[CH](CCn1ccnc1)Cn1ccnc1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 11/20 0.54
EGLN3 Q9H6Z9 1/20 0.46
CYP19A1 P11511 1/20 0.41
PRKCI P41743 1/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4429215 0.89 TBXAS1 (0.60) TBXAS1EGLN3CYP19A1PRKCICYP11B1
SCHEMBL7712328 0.79 TBXAS1 (0.55) TBXAS1EGLN3CYP19A1PRKCICYP11B1
SCHEMBL7545876 0.79 TBXAS1 (0.48) TBXAS1EGLN3CYP19A1PRKCICYP11B1
SCHEMBL7737001 0.77 TBXAS1 (0.40) TBXAS1CYP19A1CYP11B1CYP11B2
SCHEMBL6157080 0.77
SCHEMBL574077 0.77
SCHEMBL2001148 0.77
SCHEMBL28726885 0.77
SCHEMBL27687296 0.77
SCHEMBL4773938 0.77 TBXAS1 (0.75) TBXAS1EGLN3CYP19A1PRKCICYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450066-B1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMA CO LTD (JP) 1996-09-11 EP claimed