Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3733817 | 0.96 | ADRB2 (0.41) | SMN1; SMN2HTTKMT2ATDP1ADRB2 | |
| SCHEMBL8584529 | 0.94 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL2907680 | 0.94 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL6247312 | 0.92 | MAPT (0.33) | SMN1; SMN2HTTKMT2AADRB2ADRB1 | |
| SCHEMBL11041022 | 0.90 | ALDH1A1 (0.39) | SMN1; SMN2HTTKMT2ATDP1ADRB2 | |
| SCHEMBL2835530 | 0.89 | ALDH1A1 (0.41) | KMT2AADRB2ADRB1ADRB3EPHX2 | |
| SCHEMBL11037986 | 0.89 | ALDH1A1 (0.38) | ADRB2ADRB1ADRB3EPHX2ALDH1A1 | |
| SCHEMBL3152801 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTKMT2ATDP1ADRB2 | |
| SCHEMBL9776380 | 0.87 | ALDH1A1 (0.41) | ADRB2ADRB1ADRB3EPHX2ALDH1A1 | |
| SCHEMBL3733393 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2HTTKMT2ATDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |