Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573009 | 0.92 | KDR (0.42) | KDRTBXAS1SMPD1TLR8PTGS1 | |
| SCHEMBL1229601 | 0.91 | KDR (0.40) | KDRTBXAS1SMPD1TLR8PTGS1 | |
| SCHEMBL1011975 | 0.81 | KDR (0.36) | KDRTBXAS1TLR8KCNH2HRH4 | |
| SCHEMBL1011560 | 0.81 | KDR (0.36) | KDRTBXAS1TLR8KCNH2HRH4 | |
| SCHEMBL21634161 | 0.79 | KDR (0.36) | KDRKCNH2 | |
| SCHEMBL21634173 | 0.78 | LMNA (0.39) | KDR | |
| SCHEMBL23578174 | 0.78 | KDR (0.41) | KDRTBXAS1SMPD1TLR8PTGS1 | |
| SCHEMBL23578243 | 0.78 | KDR (0.44) | KDRTBXAS1SMPD1PTGS1PTGS2 | |
| SCHEMBL28824665 | 0.78 | HTR2A (0.38) | KDRTBXAS1KCNH2ALDH1A1HPGD | |
| SCHEMBL28953187 | 0.74 | KDR (0.43) | KDRTBXAS1SMPD1TLR8PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |