Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573009 | 0.98 | KDR (0.42) | KDRTLR8TBXAS1SMPD1PTGS1 | |
| SCHEMBL9036100 | 0.91 | KDR (0.38) | KDRTLR8TBXAS1SMPD1PTGS1 | |
| SCHEMBL1011975 | 0.86 | KDR (0.36) | KDRTLR8TBXAS1KCNH2 | |
| SCHEMBL1011560 | 0.86 | KDR (0.36) | KDRTLR8TBXAS1KCNH2 | |
| SCHEMBL21634161 | 0.84 | KDR (0.36) | KDRKCNH2 | |
| SCHEMBL21634173 | 0.83 | LMNA (0.39) | KDR | |
| SCHEMBL23578174 | 0.82 | KDR (0.41) | KDRTLR8TBXAS1SMPD1PTGS1 | |
| SCHEMBL28824665 | 0.82 | HTR2A (0.38) | KDRTBXAS1KCNH2 | |
| SCHEMBL23578243 | 0.82 | KDR (0.44) | KDRTBXAS1SMPD1PTGS1PTGS2 | |
| SCHEMBL21634179 | 0.79 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2461688-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| CN-104356177-A | Pesticidal compositions | DOW AGROSCIENCES LLC | 2015-02-18 | — | — | CN | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| EP-1732904-A4 | DIARYLTRIAZOLES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 | MERCK & CO INC (US) | 2007-11-14 | — | — | EP | disclosed |
| CN-1938286-A | Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | MERCK & CO INC (US) | 2007-03-28 | — | — | CN | disclosed |
| EP-1732904-A1 | DIARYLTRIAZOLES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 | Merck & Co., Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| US-RE38962-E1 | Diphenyl-triazole derivatives and their use as anti-gestative immuno-suppressant and anti-tumoral agents | GEANGE LTD. (IE) | 2006-01-31 | — | — | US | disclosed |
| WO-2005097759-A1 | DIARYLTRIAZOLES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 | MERCK & CO., INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-6333343-B1 | HETEROCYCLIC, AROMATIC COMPOUNDS AND ANTITUMOR AGENTS | GEANGE LTD. (IE) | 2001-12-25 | — | — | US | disclosed |
| EP-0986544-A1 | DIPHENYL-TRIAZOLE DERIVATIVES AND THEIR USE AS ANTI-GESTATIVE, IMMUNO-SUPPRESSANT AND ANTI-TUMORAL AGENTS | Geange Ltd. (IE) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055463-A1 | DIPHENYL-TRIAZOLE DERIVATIVES AND THEIR USE AS ANTI-GESTATIVE, IMMUNO-SUPPRESSANT AND ANTI-TUMORAL AGENTS | GEANGE LTD. (IE) | 1998-12-10 | — | — | WO | disclosed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDR 4680/4885TLR8 4763/4885TBXAS1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.