Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035160 | 0.78 | KMT2A (0.62) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9036335 | 0.76 | MEN1 (0.51) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8872843 | 0.71 | CES1 (0.43) | ALDH1A1TSHRVCAM1TDP1MAPK1 | |
| SCHEMBL4748791 | 0.69 | MEN1 (0.43) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL13993102 | 0.67 | ALDH1A1 (0.38) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL3925661 | 0.66 | HTR2A (0.49) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9036456 | 0.66 | ACHE (0.42) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9035276 | 0.66 | MAPT (0.54) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL6200472 | 0.65 | MAPT (0.57) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9194645 | 0.64 | TSHR (0.61) | MEN1KMT2AMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |