⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885127 | 0.81 | — | — | |
| SCHEMBL21145432 | 0.81 | — | — | |
| SCHEMBL21145442 | 0.81 | — | — | |
| SCHEMBL293205 | 0.77 | — | — | |
| SCHEMBL2977209 | 0.74 | — | — | |
| SCHEMBL294367 | 0.74 | CYP1A2 (0.40) | — | |
| SCHEMBL9044441 | 0.74 | VEGFA (0.37) | — | |
| SCHEMBL21591048 | 0.73 | — | — | |
| SCHEMBL4065310 | 0.73 | — | — | |
| SCHEMBL236633 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |