Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101486 | 0.94 | TERT (0.39) | VEGFAEGLN1TERTS1PR1S1PR3 | |
| SCHEMBL5424648 | 0.83 | — | — | |
| SCHEMBL5428965 | 0.83 | — | — | |
| SCHEMBL1406334 | 0.83 | — | — | |
| SCHEMBL20999795 | 0.81 | ALDH1A1 (0.49) | VEGFAEGLN1L3MBTL1S1PR1S1PR3 | |
| SCHEMBL6629974 | 0.81 | ALDH1A1 (0.49) | VEGFAEGLN1L3MBTL1S1PR1S1PR3 | |
| SCHEMBL6636120 | 0.81 | S1PR1 (0.41) | VEGFAEGLN1L3MBTL1POLBTERT | |
| SCHEMBL25379496 | 0.79 | VEGFA (0.37) | VEGFAEGLN1L3MBTL1POLBTERT | |
| Iodide SCHEMBL22034640 | 0.78 | VEGFA (0.36) | VEGFAEGLN1L3MBTL1POLBTERT | |
| Iodide SCHEMBL22034682 | 0.78 | VEGFA (0.36) | VEGFAEGLN1L3MBTL1POLBTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |