Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570178 | 1.00 | KMT2A (0.40) | KMT2AARG1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL6432107 | 0.81 | KMT2A (0.38) | KMT2AARG1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL6432101 | 0.81 | KMT2A (0.38) | KMT2AARG1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL15046738 | 0.81 | KMT2A (0.38) | KMT2AARG1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL2425461 | 0.80 | MAPK1 (0.34) | — | |
| SCHEMBL6161938 | 0.80 | MAPK1 (0.34) | — | |
| SCHEMBL9645913 | 0.80 | LMNA (0.36) | KMT2A | |
| SCHEMBL2425462 | 0.80 | MAPK1 (0.34) | — | |
| SCHEMBL9645916 | 0.80 | LMNA (0.36) | KMT2A | |
| SCHEMBL13534665 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060914-A2 | PENICILLAMINE AND ITS DERIVATIVES ARE USED IN THE TREATMENT OF COPPER TOXICITY AND NASH | Krisani Biosciences (P) Ltd. (IN) | 2017-04-13 | — | — | WO | disclosed |
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| CN-1028229-C | Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical composition containing same and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1995-04-19 | — | — | CN | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| CN-1049159-A | The heterogeneous ring compound of new nitrogenous and sulphur, the method that contains the pharmaceutical composition of this compounds and prepare them | RICHTER GEDEON VEGYESZET (HU) | 1991-02-13 | — | — | CN | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |
| US-4283407-A | ANTIHYPERTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-08-11 | — | — | US | disclosed |