Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645913 | 1.00 | LMNA (0.36) | LMNAMAPTALDH1A1KDM4EPPM1B | |
| SCHEMBL7417762 | 1.00 | LMNA (0.36) | LMNAMAPTALDH1A1KDM4EPPM1B | |
| SCHEMBL14570224 | 0.81 | TSHR (0.34) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL14596799 | 0.81 | TSHR (0.34) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9036688 | 0.80 | KMT2A (0.40) | KMT2A | |
| SCHEMBL6161938 | 0.76 | MAPK1 (0.34) | — | |
| SCHEMBL2425462 | 0.76 | MAPK1 (0.34) | — | |
| SCHEMBL11086400 | 0.74 | TRPA1 (0.36) | LMNAALDH1A1KDM4E | |
| SCHEMBL951739 | 0.74 | HTT (0.35) | KMT2A | |
| SCHEMBL950964 | 0.74 | HTT (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |