Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037238 | 0.75 | SMN1; SMN2 (0.34) | ALDH1A1 | |
| SCHEMBL3558911 | 0.73 | KDM4E (0.33) | KDM4E | |
| SCHEMBL11868456 | 0.71 | CHEK1 (0.36) | ALDH1A1KDM4E | |
| SCHEMBL21642536 | 0.63 | SMN1; SMN2 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL23143355 | 0.60 | ALK (0.42) | KDM4E | |
| SCHEMBL11869822 | 0.59 | SMN1; SMN2 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL9039022 | 0.59 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL21541915 | 0.58 | — | — | |
| SCHEMBL14829051 | 0.58 | HRH4 (0.40) | — | |
| SCHEMBL12675667 | 0.58 | FGFR1 (0.33) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518530-B1 | Improvements in or relating to excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5196421-A | Treatment of neurological disorders | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0518530-A2 | Improvements in or relating to excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5153196-A | Administering for reduction of neurotransmission in nervous system disorders | ELI LILLY AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |