SCHEMBL3558911

SCHEMBL3558911

Clc1cc(Cl)c2c(c1)nnc1nncn12

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CHEK1 O14757 1/20 0.32
LIMK1 P53667 1/20 0.32
MAPK14 Q16539 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
PARP15 Q460N3 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036896 0.73 ALDH1A1 (0.32) KDM4E
SCHEMBL9037238 0.58 SMN1; SMN2 (0.34) PARP15TNKS2PARP2SMN1; SMN2
SCHEMBL11471893 0.56 SRC (0.40) KDM4ESMN1; SMN2
SCHEMBL23577370 0.54 HRH4 (0.43) KDM4EPARP15TNKS2PARP2SMN1; SMN2
SCHEMBL2937097 0.50 TSHR (0.67) KDM4EMAPK14SMN1; SMN2
SCHEMBL11804640 0.50 PIK3R1 (0.45) SMN1; SMN2
SCHEMBL9039022 0.49 ALDH1A1 (0.44) SMN1; SMN2
SCHEMBL23022756 0.48 KMT2A (0.39) KDM4EPARP15TNKS2PARP2SMN1; SMN2
SCHEMBL25225154 0.48 SMN1; SMN2 (0.35) KDM4EPARP15TNKS2PARP2SMN1; SMN2
SCHEMBL358001 0.48 ALDH1A1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838672-B2 Use of fused ring-1,2,4-benzotriazine derivatives as herbicides or plant growth regulators for the control of undesired plants or vegetation, compounds and compositions thereof, and processes for their preparation BAYER CROPSCIENCE GMBH (DE) 2010-11-23 US disclosed
US-20070042909-A1 Use of fused ring-1,2,4-benzotriazine derivatives as herbicides or plant growth regulators for the control of undesired plants or vegetation, compounds and compositions thereof, and processes for their preparation BAYER CROPSCIENCE GMBH (DE) 2007-02-22 US disclosed
EP-1651650-A1 THE USE OF FUSED RING-1,2,4-BENZOTRIAZINE DERIVATIVES AS HERBICIDES OR PLANT GROWTH REGULATORS FOR THE CONTROL OF UNDESIRED PLANTS OR VEGETATION, COMPOUNDS AND COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR PREPARATION Bayer CropScience GmbH (DE) 2006-05-03 EP disclosed
WO-2005014595-A1 THE USE OF FUSED RING-1,2,4-BENZOTRIAZINE DERIVATIVES AS HERBICIDES OR PLANT GROWTH REGULATORS FOR THE CONTROL OF UNDESIRED PLANTS OR VEGETATION, COMPOUNDS AND COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR PREPARATION BAYER CROPSCIENCE GMBH (DE) 2005-02-17 WO disclosed
EP-1502918-A1 The use of fused ring-1,2,4-benzotriazine derivatives as herbicides or plant growth regulators for the control of undesired plants or vegetation, compounds and compositions thereof, and processes for their preparation Bayer CropScience GmbH (DE) 2005-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042909-A1 Use of fused ring-1,2,4-benzotriazine derivatives as herbicides or plant growth regulators for the control of undesired plants or vegetation, compounds and compositions thereof, and processes for their preparation BROX, CYP4X1, ZFX KDM4E 763/4885CHEK1 4058/4885LIMK1 3417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.