SCHEMBL9037007

SCHEMBL9037007

CON=Cc1c(Cl)ccc(-n2c(=O)[nH]c(C(F)(F)F)c(N)c2=O)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
BCAT2 O15382 1/20 0.32
BCAT1 P54687 1/20 0.32
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8120948 0.80 BCAT1 (0.54) BCAT2BCAT1
SCHEMBL8120947 0.80 BCAT1 (0.54) BCAT2BCAT1
SCHEMBL8113529 0.73 EGFR (0.31) EGFRERBB2
SCHEMBL8113528 0.73 EGFR (0.31) EGFRERBB2
SCHEMBL9037436 0.72 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL9038251 0.71
SCHEMBL8612848 0.71 TP53 (0.34) L3MBTL1BCAT2BCAT1
SCHEMBL9037994 0.70 TP53 (0.36) BCAT2BCAT1
SCHEMBL7162422 0.70 BCAT1 (0.33) BCAT2BCAT1
SCHEMBL9038745 0.69 BCAT1 (0.34) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716653-A1 SUBSTITUTED 1-AMINO-3-PHENYLURACILS WITH HERBICIDAL ACTIVITIES BASF AKTIENGESELLSCHAFT (DE) 1996-06-19 EP disclosed
WO-1995006641-A1 SUBSTITUTED 1-AMINO-3-PHENYLURACILS WITH HERBICIDAL ACTIVITIES BASF AKTIENGESELLSCHAFT (DE) 1995-03-09 WO disclosed