Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533970 | 0.93 | ALDH1A1 (0.44) | EPHX1ALDH1A1PDK1PDE8BSMN1; SMN2 | |
| SCHEMBL476913 | 0.81 | ALDH1A1 (0.49) | EPHX1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL18833108 | 0.81 | NOS1 (0.36) | EPHX1SMN1; SMN2USP2TP53HPGD | |
| SCHEMBL27732568 | 0.77 | EPHX1 (0.37) | EPHX1ALDH1A1SMN1; SMN2USP2TP53 | |
| SCHEMBL4347775 | 0.77 | ALDH1A1 (0.55) | EPHX1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3684346 | 0.75 | USP2 (0.38) | EPHX1ALDH1A1SMN1; SMN2USP2TP53 | |
| SCHEMBL13283249 | 0.75 | EPHX1 (0.63) | EPHX1ALDH1A1PDK1PDE8BSMN1; SMN2 | |
| SCHEMBL2716830 | 0.75 | EPHX1 (0.63) | EPHX1ALDH1A1PDK1PDE8BSMN1; SMN2 | |
| SCHEMBL10850965 | 0.73 | EPHX1 (0.47) | EPHX1ALDH1A1PDK1PDE8BTDP1 | |
| SCHEMBL5922580 | 0.73 | EPHX1 (0.61) | EPHX1ALDH1A1PDK1PDE8BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |