SCHEMBL903716

SCHEMBL903716

c1ccc(-c2ccc(-c3nc4cc5oc(-c6ccc(-c7ccccc7)cc6)nc5cc4o3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.64
RAB9A P51151 8/20 0.64
SMN1; SMN2 Q16637 7/20 0.64
KDM4E B2RXH2 5/20 0.64
HPGD P15428 4/20 0.64
CASP3 P42574 3/20 0.64
SENP7 Q9BQF6 3/20 0.64
SENP6 Q9GZR1 3/20 0.64
POLB P06746 2/20 0.64
SENP8 Q96LD8 2/20 0.64
ALDH1A1 P00352 5/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
MAPT P10636 4/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ESR1 P03372 3/20 0.53
ESR2 Q92731 3/20 0.53
GAA P10253 2/20 0.53
ATM Q13315 1/20 0.53
GFER P55789 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9018554 0.96 NPC1 (0.68) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL26745185 0.92 NPC1 (0.60) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL15413714 0.90 NPC1 (0.66) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL19601391 0.89 NPC1 (0.76) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL2244575 0.89 SMN1; SMN2 (0.70) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL7905531 0.89 SMN1; SMN2 (0.70) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL29819610 0.89 GPR119 (0.61) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL590701 0.89 GPR119 (0.61) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL29820037 0.89 GPR119 (0.61) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13528498 0.86 NPC1 (0.72) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE45850-E1 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX K.K. (JP) 2016-01-19 US disclosed
US-RE45850-E1 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX K.K. (JP) 2016-01-19 US disclosed
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
US-8512824-B2 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX KK (JP) 2013-08-20 US disclosed
US-8512824-B2 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX KK (JP) 2013-08-20 US disclosed
EP-2331655-B1 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2013-07-03 EP disclosed
US-20120113380-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-10 US disclosed
US-20120099052-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 US disclosed
US-20120099052-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 US disclosed
WO-2012052950-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 WO disclosed
WO-2012044867-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 WO disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
US-20100085521-A1 Composition of Organic Compounds, Optical Film and Method of Production Thereof CRYSOPTIX KK (JP) 2010-04-08 US disclosed
US-20100085521-A1 Composition of Organic Compounds, Optical Film and Method of Production Thereof CRYSOPTIX KK (JP) 2010-04-08 US disclosed
WO-2010020928-A2 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2010-02-25 WO disclosed