SCHEMBL9018554

SCHEMBL9018554

c1ccc(-c2nc3cc4oc(-c5ccccc5)nc4cc3o2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.68
RAB9A P51151 8/20 0.68
SMN1; SMN2 Q16637 7/20 0.68
KDM4E B2RXH2 5/20 0.68
HPGD P15428 4/20 0.68
CASP3 P42574 3/20 0.68
SENP7 Q9BQF6 3/20 0.68
SENP6 Q9GZR1 3/20 0.68
POLB P06746 2/20 0.68
SENP8 Q96LD8 2/20 0.68
ALDH1A1 P00352 5/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
MAPT P10636 4/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HDAC6 Q9UBN7 1/20 0.55
ELANE P08246 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903716 0.96 NPC1 (0.64) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL15413714 0.94 NPC1 (0.66) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL26745313 0.90 SMN1; SMN2 (0.67) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL9683245 0.90 NPC1 (0.62) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14193959 0.89 SMN1; SMN2 (0.66) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL19601391 0.89 NPC1 (0.76) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL26745185 0.88 NPC1 (0.60) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL18583160 0.87 SMN1; SMN2 (0.68) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL21166566 0.86 NPC1 (0.54) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL13528498 0.86 NPC1 (0.72) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
US-20220119596-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-04-21 US disclosed
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2021-07-01 US disclosed
US-11047166-B2 Glass panel unit PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2021-06-29 US disclosed
US-10619403-B2 Glass panel unit PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2020-04-14 US disclosed
US-20190136608-A1 GLASS PANEL UNIT PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2019-05-09 US disclosed
US-20170328122-A1 GLASS PANEL UNIT PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2017-11-16 US disclosed
US-20170328122-A1 GLASS PANEL UNIT PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2017-11-16 US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 US disclosed
US-9793492-B2 Compound, light emitter, and organic light emitting device KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-10-17 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
US-5558904-A Electroluminescent devices containing a conjugated polymer obtained via halogen precursor route chemistry XEROX CORPORATION (US) 1996-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE DDT, DRD1, DRD2 NPC1 3198/4885RAB9A 1696/4885SMN1; SMN2 4840/4885
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 NPC1 1759/4885RAB9A 1666/4885SMN1; SMN2 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.